Table 1.
Patients characteristics
Characteristics | N = 111 |
---|---|
Age | |
Years | 65 (40-80) |
Sex, n (%) | |
F | 45 (40.5) |
M | 66 (59.5) |
Performance status, n (%) | |
0 | 64 (57.7) |
1 | 43 (38.7) |
2 | 4 (3.6) |
Tumor location, n (%) | |
Rectum | 32 (28.8) |
Right colon | 34 (30.6) |
Left colon | 45 (40.5) |
Primary tumor resection, n (%) | |
Yes | 67 (60.4) |
No | 44 (39.6) |
Grading, n (%) | |
1 | 4 (3.6) |
2 | 41 (37) |
3 | 20 (18) |
NA | 46 (41.4) |
Mucinous histology, n (%) | |
Yes | 18 (16.2) |
No | 79 (71.2) |
NA | 14 (12.6) |
Microsatellite instability, n (%) | |
MSI | 0 (0) |
MSS | 61 (55) |
NA | 50 (45) |
Metastatic disease at initial diagnosis, n (%) | |
Yes | 73 (65.8) |
No | 38 (34.2) |
Number of metastatic sites, n (%) | |
<3 | 79 (71.2) |
≥3 | 32 (28.8) |
Liver metastasis, n (%) | |
Yes | 71 (64) |
No | 40 (36) |
Lung metastasis, n (%) | |
Yes | 46 (41.4) |
No | 65 (58.6) |
Peritoneal metastasis, n (%) | |
Yes | 21 (18.9) |
No | 90 (81.1) |
Nodes metastasis, n (%) | |
Yes | 19 (17.1) |
No | 92 (82.9) |
CEA levels, n (%) | |
<5 | 18 (16.2) |
≥5 | 68 (61.3) |
NA | 25 (22.5) |
Type of first-line treatment, n (%) | |
Oxaliplatin-based doublet | 66 (59.5) |
Irinotecan-based doublet | 29 (26.1) |
FOLFOXIRI triplet | 16 (14.4) |
Antiangiogenic use in combination with first-line chemotherapy, n (%) | |
Yes | 80 (66.1) |
No | 31 (33.9) |
CEA, carcinoembryonic antigen; F, female; M, male; MSI, microsatellite instability: MSS, microsatellite stable. NA, not available.