Table 4.
The DALYs cases and ASR of DALYs of Alzheimer's disease and other dementias in 1990 and 2019 and its EAPC.
| 1990 | 2019 | 1990–2019 | |||
|---|---|---|---|---|---|
| Characteristics |
DALYs (*10∧6) (95% UI) |
ASR of DALYs (per 100,000) (95% UI) |
DALYs (*10∧6) (95% UI) |
ASR of DALYs (per 100,000) (95% UI) |
EAPC of ASR of DALYs (95% CI) |
| Global | 9.66 (4.23–21.37) | 326.71 (143.33–731.03) | 25.28 (11.2–54.56) | 338.64 (151.02–731.27) | 0.15 (0.13 to 0.16) |
| Gender | |||||
| Males | 3.39 (1.45–7.83) | 289.24 (123.24–660.87) | 9.37 (4.02–21.1) | 304.47 (130.97–679.76) | 0.21 (0.2 to 0.23) |
| Females | 6.27 (2.77–13.77) | 347.87 (154.52–765.02) | 15.9 (7.16–33.81) | 361.2 (162.8–767.72) | 0.15 (0.13 to 0.17) |
| Sociodemographic index | |||||
| Low | 0.39 (0.16–0.91) | 295.19 (121.35–694.71) | 1.04 (0.43–2.45) | 315.76 (129.02–742.9) | 0.28 (0.26 to 0.3) |
| Low-middle | 1.01 (0.43–2.41) | 287.22 (118.6–672.6) | 3.07 (1.28–7.06) | 304.76 (126.52–702.3) | 0.2 (0.18 to 0.23) |
| Middle | 2.2 (0.92–5.13) | 335.33 (139.18–770.43) | 6.69 (2.84–15.09) | 346.11 (148.62–770.18) | 0.14 (0.12 to 0.16) |
| High-middle | 2.71 (1.19–5.92) | 335.16 (148.39–736.45) | 6.81 (3.08–14.82) | 348.46 (157.71–754.37) | 0.18 (0.13 to 0.22) |
| High | 3.35 (1.53–7.31) | 324.07 (147.34–705.64) | 7.66 (3.56–15.74) | 332.4 (155–688.29) | 0.11 (0.08 to 0.13) |
| 21 GBD regions | |||||
| Central Asia | 0.12 (0.06–0.27) | 326.32 (149.38–721.24) | 0.16 (0.07–0.35) | 345.47 (155.28–775.08) | 0.19 (0.16 to 0.21) |
| Central Europe | 0.42 (0.19–0.94) | 349.87 (156.52–778.96) | 0.79 (0.37–1.69) | 348.75 (160.87–734.47) | −0.04 (−0.05 to −0.02) |
| Eastern Europe | 0.68 (0.31–1.51) | 305.52 (140.31–679.46) | 1.14 (0.53–2.49) | 324.8 (149.89–705.23) | 0.23 (0.21 to 0.25) |
| Australasia | 0.07 (0.03–0.15) | 326.93 (147.01–726.32) | 0.18 (0.08–0.39) | 319.88 (146.31–681.98) | −0.09 (−0.11 to −0.07) |
| High-income Asia Pacific | 0.54 (0.24–1.18) | 322.6 (143.99–710.51) | 2.37 (1.1–4.85) | 385.38 (179.3–791.75) | 0.81 (0.7 to 0.92) |
| High-income North America | 1.24 (0.59–2.63) | 330.78 (158–700.92) | 2.27 (1.1–4.7) | 317.66 (154.02–653.15) | −0.22 (−0.27 to −0.17) |
| Southern Latin America | 0.12 (0.05–0.26) | 304.44 (137–674.68) | 0.27 (0.12–0.59) | 311.86 (142.12–674.17) | 0.13 (0.11 to 0.14) |
| Western Europe | 1.85 (0.84–4.05) | 317.02 (141.51–693.85) | 3.58 (1.64–7.58) | 309.71 (141.53–663.69) | −0.08 (−0.1 to −0.06) |
| Andean Latin America | 0.05 (0.02–0.12) | 306.69 (127.33–718.29) | 0.16 (0.07–0.36) | 312.67 (133.67–691.68) | 0.09 (0.08 to 0.11) |
| Caribbean | 0.07 (0.03–0.15) | 295.98 (122.92–684.98) | 0.16 (0.07–0.34) | 299.45 (126.93–661.71) | 0.06 (0.05 to 0.07) |
| Central Latin America | 0.21 (0.09–0.49) | 329.17 (133.63–765.75) | 0.73 (0.3–1.63) | 333.23 (136.24–747.25) | 0.03 (0.01 to 0.04) |
| Tropical Latin America | 0.24 (0.1–0.55) | 384.41 (163.84–871.32) | 0.87 (0.38–1.91) | 390.88 (172.01–855.99) | 0.11 (0.08 to 0.15) |
| North Africa and Middle East | 0.44 (0.19–0.98) | 391.32 (170.34–883.07) | 1.21 (0.53–2.67) | 386.96 (171.95–848.51) | −0.03 (−0.04 to −0.01) |
| South Asia | 0.73 (0.3–1.73) | 238.2 (96.13–575.6) | 2.62 (1.06–6.23) | 262.09 (105.55–617.38) | 0.32 (0.25 to 0.39) |
| East Asia | 1.91 (0.79–4.46) | 347.44 (143.95–798.77) | 6.2 (2.78–13.58) | 366.61 (164.75–789.1) | 0.25 (0.21 to 0.3) |
| Oceania | 0.01 (0–0.01) | 332.94 (136.7–765.18) | 0.01 (0.01–0.03) | 318.77 (133.77–726.91) | −0.18 (−0.21 to −0.15) |
| Southeast Asia | 0.57 (0.23–1.32) | 333.58 (136.46–764.32) | 1.55 (0.63–3.43) | 342.18 (141.51–765.11) | 0.09 (0.07 to 0.1) |
| Central Sub-Saharan Africa | 0.04 (0.02–0.09) | 347.02 (149.92–796.7) | 0.11 (0.05–0.26) | 380.57 (165.07–857.23) | 0.35 (0.33 to 0.37) |
| Eastern Sub-Saharan Africa | 0.14 (0.06–0.31) | 323.31 (135.15–746.55) | 0.35 (0.15–0.82) | 356 (144.97–829.93) | 0.4 (0.37 to 0.43) |
| Southern Sub-Saharan Africa | 0.06 (0.03–0.15) | 313.71 (135.09–712.18) | 0.13 (0.06–0.3) | 323.81 (138.29–740.97) | 0.1 (0.06 to 0.13) |
| Western Sub-Saharan Africa | 0.17 (0.07–0.42) | 309.39 (124–769.07) | 0.4 (0.16–0.93) | 333.53 (129.48–774.76) | 0.35 (0.3 to 0.4) |
DALYs, disability-adjusted life-years; ASR, age-standardized rate; EAPC, estimated annual percent change; SDI, sociodemographic index.