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. 2022 Oct 10;9:969243. doi: 10.3389/fmed.2022.969243

Table 4.

Relationship between sputum eosinophils and AHR in asthmatic populations.

Asthma population Patient number (N), [REF] Allergen Methacholine Mean PC20 mg/ml Mean (SE) sputum Eos (%) Correlation
Mild intermittent (recent diagnosis) N = 30, [Boulet LP] Cat, dog, house-dust mite or cockroach 4.9 (2.3) 0.9 (0.5–2.2) NO
Mild intermittent (diagnosis > 5 years) N = 30, [Boulet LP] Cat, dog, house-dust mite or cockroach 2.9 (2.2) 0.9 (0.4–1.9) NO
Mild persistent
Off ICS treatment (6 month)
N = 30, [Foresi A] House-dust mite 0.42 to 2.6 mmol 16.7 ± 5.06 YES r =-0.52
Mild to moderate persistent
Off ICS treatment (1 month)
N = 28 [Crimi E] House-dust mite or pet dandruff 0.099 8.5± 1.9 NO R = 0.24
Mild to moderate naïve
Off ICS treatment (6 weeks)
N = 118,[ R. Louis] House-dust mites, grass, birch, weed, cat and dog dander, mold mixture 1.10 (0.03–16) 10.9 (13.6) YES R =-0.40
Mild to moderate naïve
Off ICS treatment (3 months)
N = 35 [A Jatakanon] Non known 0.52 (1.23) 6.8 (1.2) YES r = −0.40