Figure 3.

Significantly enriched biological pathways

(A–C) Selected groups of enriched biological pathways (q ≤ 0.5) for pairwise comparisons among CTRL, PD, and T2D, specifically, (A) PD-CTRL, (B) T2D-CTRL, and (C) T2D-PD. Colored triangles indicate statistical significance (q < 0.05) and direction. Rows represent pathways, panels represent pairwise comparisons, and columns within panels represent tissues. The database of origin for each pathway is noted with a suffix R or K for Reactome or Kyoto Encyclopedia of Genes and Genomes (KEGG), respectively. GP1b-IX-V, glycoprotein Ib-IX-V; SREBP, sterol regulatory element binding protein.