TABLE 2.

Differences of amplitude of low-frequency fluctuation (ALFF) values in three frequency bands among the groups.

Contrast	Brain regions	BA	Volume (mm3)	MNI coordinates			t-value
				X	Y	Z
1. Conventional frequency band
PD-A vs. HCs	PD-A < HCs
	left insula	48	2619	−39	15	−3	−4.1
	right anterior cingulate gyri	32	7155	6	45	24	−5.1
PD-A vs. PD-NA	NA
PD-NA vs. HCs	PD-NA < HCs
	left inferior temporal gyrus	20	4158	−42	−30	−24	−4.9
2. Slow-4 band
PD-A vs. HCs	PD-A < HCs
	right anterior cingulate gyri	32	3726	6	45	24	−4.7
	left superior frontal gyrus	10	2079	−21	57	12	−4.7
PD-A vs. PD-NA	NA
PD-NA vs. HCs	PD-NA < HCs
	left inferior temporal gyrus	20	4428	−42	−30	−24	−5.3
3. Slow-5 band
PD-A vs. HCs	PD-A > HCs
	right middle temporal gyrus	22	3132	57	−33	6	4.8
	left middle occipital gyrus	19	2835	−36	−81	15	4.2
	PD-A < HCs
	left anterior cingulate gyri	32	5022	−9	39	12	−4.4
PD-A vs. PD-NA	PD-A < PD-NA
	right anterior cingulate gyri	32	1701	3	45	27	−4.0
PD-NA vs. HCs	NA

BA, Brodmann’s area; MNI, Montreal Neurological Institute; PD-A, Parkinson’s disease with apathy; PD-NA, Parkinson’s disease without apathy; HCs, healthy controls; NA, Not applicable; - no significant clusters detected.