Table 2.
Non-redundant ESPs, identified with confidence, exclusive to B. glabrata SCW from snails that were naïve and at 16h-, 1W-, 2W- and 3W-PME to S. mansoni miracidia.
| Time-point post-miracidia exposure | Accession No. | Description | −10lgP | Coverage (%) a | No. of peptides | No. unique b | BLASTp e-value |
|---|---|---|---|---|---|---|---|
| 16h | BGLB004262-PB | ganglioside GM2 activator-like | 23.68 | 4 | 1 | 1 | 6.22E-152 |
| BGLB008634-PB | AP-3 complex subunit beta-2-like | 18.86 | 1 | 1 | 1 | 0 | |
| BGLB009288-PB | multiple EGF and TSP domain-containing protein | 15.95 | 2 | 1 | 1 | 0 | |
| BGLB012280-PB | tissue factor pathway inhibitor isoform X2 | 44.84 | 32 | 3 | 3 | 2.04E-45 | |
| BGLB016060-PA | bactericidal permeability-increasing protein-like | 117.2 | 23 | 11 | 9 | 0 | |
| BGLB017086-PA | Hypothetical predicted protein | 22.59 | 6 | 2 | 2 | 0 | |
| BGLB021854-PA | CD109 antigen | 29.06 | 2 | 2 | 2 | 0 | |
| BGLB026410-PA | chorion peroxidase-like | 42.64 | 5 | 2 | 2 | 0 | |
| BGLB030199-PA | L-amino acid oxidase-like | 19.3 | 5 | 1 | 1 | 3.56E-122 | |
| BGLB033580-PA | serpin family protein | 62.78 | 12 | 5 | 5 | 0 | |
| BGLB035660-PA | Bsmp protein | 38.61 | 7 | 2 | 2 | 0 | |
| BGLB036153-PA | uncharacterized protein LOC106069469, partial | 44.72 | 11 | 3 | 3 | 2.96E-105 | |
| BGLB037955-PA | golgin subfamily a member 4 | 17.59 | 0 | 1 | 1 | 0 | |
| BGLB040188-PA | lipopolysaccharide-binding protein | 120.97 | 31 | 11 | 9 | 5.39E-164 | |
| 1W | BGLB008299-PB | actin-5C | 49.62 | 5 | 2 | 2 | 0 |
| BGLB011796-PB | progranulin-like isoform X1 | 55.8 | 2 | 1 | 1 | 0 | |
| BGLB011796-PC | fibrillin-1 isoform X1 | 55.8 | 2 | 1 | 1 | 0 | |
| BGLB021817-PA | polyubiquitin-B isoform X2 | 16.08 | 6 | 1 | 1 | 1.76E-104 | |
| BGLB035643-PA | uncharacterized protein LOC106055144 | 30.4 | 8 | 1 | 1 | 7.28E-80 | |
| 2W | BGLB000141-PA | microfibril-associated glycoprotein 4-like | 37.26 | 7 | 3 | 3 | 0 |
| BGLB016967-PA | calmodulin-like protein 5 isoform X3 | 41.59 | 10 | 1 | 1 | 9.67E-82 | |
| BGLB019617-PA | uncharacterized protein LOC106050984 | 48.27 | 11 | 1 | 1 | 1.64E-54 | |
| BGLB031523-PB | uncharacterized protein LOC106067104 isoform X3 | 69.5 | 12 | 2 | 2 | 4.40E-137 | |
| BGLB034051-PA | uncharacterized protein LOC106054319 | 21.21 | 6 | 1 | 1 | 2.59E-116 | |
| BGLB040281-PA | Zinc metalloproteinase/disintegrin | 36.23 | 3 | 1 | 1 | 0 | |
| 3W | BGLB000016-PA | biomphalysin 8 | 24.5 | 2 | 1 | 1 | 0 |
| BGLB000033-PA | biomphalysin 2 | 131.13 | 17 | 10 | 8 | 0 | |
| BGLB005531-PC | kazrin-like isoform X1 | 19.44 | 1 | 1 | 1 | 0 | |
| BGLB014188-PB | serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like | 17.05 | 1 | 1 | 1 | 0 | |
| BGLB026487-PA | HEAT repeat domain-containing protein | 67.97 | 6 | 2 | 2 | 0 | |
| BGLB026513-PB | uncharacterized protein LOC106063245 isoform X1 | 26.91 | 5 | 1 | 1 | 4.01E-92 | |
| BGLB027975-PA | uncharacterized protein LOC106065300 | 105.39 | 22 | 6 | 6 | 1.86E-112 | |
| BGLB028940-PA | uncharacterized protein LOC106063866 | 105.39 | 23 | 6 | 6 | 9.07E-129 | |
| BGLB029397-PA | uncharacterized protein LOC106074740 | 74.38 | 36 | 3 | 3 | 2.03E-71 | |
| BGLB030954-PA | golgin subfamily B member 1 | 17.93 | 3 | 1 | 1 | 0 | |
| BGLB031282-PA | von Willebrand factor d and egf domain-containing protein | 16.74 | 0 | 1 | 1 | 0 | |
| BGLB032561-PA | uncharacterized protein LOC106069515 | 31.78 | 10 | 1 | 1 | 3.39E-85 | |
| BGLB035882-PA | uncharacterized protein LOC106054306 (ovipostatin-like) | 41.87 | 7 | 1 | 1 | 8.73E-136 | |
| BGLB036679-PA | uncharacterized protein LOC106077041 | 17.24 | 6 | 1 | 1 | 1.91E-72 | |
| BGLB037163-PA | uncharacterized protein LOC106079133 | 97.22 | 54 | 7 | 7 | 2.59E-80 | |
| BGLB038355-PA | uncharacterized protein LOC106069514 | 74.68 | 16 | 3 | 3 | 3.78E-100 | |
| Naïve | BGLB000202-PA | biomphalysin 20 | 59.12 | 6 | 2 | 2 | 0 |
| BGLB001498-PB | calmodulin isoform X2 | 37.29 | 12 | 2 | 1 | 5.91E-119 | |
| BGLB005344-PB | beta-glucuronidase isoform X1 | 32.35 | 2 | 1 | 1 | 0 | |
| BGLB020170-PA | thioester-containing protein 1 | 23.22 | 7 | 1 | 1 | 3.05E-100 | |
| BGLB024127-PA | calmodulin, striated muscle | 16.37 | 6 | 1 | 1 | 9.23E-99 | |
| BGLB030391-PA | probable serine carboxypeptidase CPVL | 34.18 | 3 | 1 | 1 | 0 | |
| BGLB034203-PA | zinc finger ZZ-type and EF-hand domain-containing protein 1-like | 15.79 | 0 | 1 | 1 | 0 | |
| BGLB035135-PA | endothelin-converting enzyme 2-like isoform X3 | 31.14 | 2 | 1 | 1 | 0 |
a
The whole protein sequence coverage from the peptides identified with LC-MS/MS.
b
The number of identified peptides unique to the protein.
Details of coverage, peptide match number and BLAST confidence (e-value) are shown.