Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 10;9:1027223. doi: 10.3389/fmolb.2022.1027223

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Yang, Wu, Wang, Rubino, Nickels and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Time-averaged pore radius profiles of (A) the homology model and (B) the refined model. The grey shaded areas correspond to the one-sigma (dark gray) and two-sigma (light gray) confidence intervals. The pore lining residues (facing the channel more than 50% of the time) are indicated as dots colored by their hydrophobicity. Top view of the bottleneck residue PHE26 in the channel of (C) the homology model and (D) the refined model. Pore hydration profiles of (E) the homology model and (F) the refined model. Coordinates of water molecules along the z axis were plotted as a function of time. Each water molecule was represented by a blue dot.