Figure 4.

Phages ST-W77 and SE-W109 were recovered from mouse colon content, colon tissue but not spleen of Salmonella-infected mouse. All mice were orally fed with streptomycin sulfate 1 day prior to S. Tm infection (10⁸ CFU/mouse). Orally treatment with phages (10¹⁰ PFU/mouse) was started 1 h after S. Tm infection and once daily for three consecutive days. On day 4 p.i., mouse tissues were harvested for enumerated phage in each tissue (PFU/gm) by a double-layer plaque assay. Bars represent the geometric mean; error bars indicate geometric standard deviation. *** indicated p < 0.001 and ns, a non-statistically significant difference; N.D., not detectable.