TABLE 2.
Tests for heterophile antibodies
| Test | Manufacturer | Test principle |
|---|---|---|
| Paul-Bunnell-Davidsohn test | Sanofi Diagnostics Pasteur | Agglutination of horse red blood cells by presence of heterophile antibodies; absorption with Forssmann antigen and bovine red blood cell emulsion |
| Monosticon Dri-Dot | Organon Teknika | Latex agglutination based on erythrocyte antigen from horse and sheep; absorption with guinea pig kidney extract |
| Avitex-IM | Omega Diagnostics Ltd. | Latex agglutination based on reaction with bovine erythrocyte glycoprotein |
| Alexon Serascan infectious mononucleosis test | Alexon Biomedical Inc. | Latex agglutination based on selected erythrocytes from horse |
| Clearview IM | Unipath Ltd. | Direct particle-bound antigen-antibody reaction with latex-coated bovine erythrocyte glycoprotein |
| Cards±OS Mono | Pacific Biotech, Inc. | Color immunochromatographic assay; extracted beef stroma is immobilized on the membrane of the reaction unit (solid phase), and goat anti-human IgM antibody is linked to alkaline phosphatase |