Table 2.
Multivariate analysis of clinical characteristics related to LLMN.
| Variable | OR | 95% CI | p-Value |
|---|---|---|---|
| Age | 0.96 | 0.95-0.98 | <0.001* |
| Hypertension | |||
| Yes | 0.59 | 0.36-0.97 | 0.039* |
| No | Reference | – | – |
| Smoking | |||
| Yes | 1.78 | 1.09-2.92 | 0.022* |
| No | Reference | – | – |
| Tumor size | 2.63 | 1.97-3.52 | <0.001* |
| Tumor location | |||
| Upper | Reference | – | – |
| Middle | 0.40 | 0.27-0.60 | <0.001* |
| Lower | 0.31 | 0.20-0.48 | <0.001* |
| Tumor vascularity | |||
| Yes | 0.63 | 0.43-0.91 | 0.015* |
| No | Reference | – | – |
| Capsular dorsal invasion | |||
| Yes | 2.90 | 1.23-6.81 | 0.015* |
| No | Reference | – | – |
| LNs size | 1.45 | 1.11-1.88 | 0.006* |
| Irregular LNs morphology | |||
| Yes | 1.75 | 1.14-2.68 | 0.01* |
| No | Reference | – | – |
| Abnormal lymphatic portal structure | |||
| Yes | 0.56 | 0.36-0.85 | 0.007* |
| No | Reference | – | – |
| LNs microcalcification | |||
| Yes | 1.87 | 1.32-2.66 | <0.001* |
| No | Reference | – | – |
| LNs vascularity | |||
| Yes | 2.20 | 1.55-3.13 | <0.001* |
| No | Reference | – | – |
* means p-value< 0.05. LNs, lymph nodes.