TABLE 1.
Pneumococcal antisera used in the inhibition EIA and in the EIA for antibody to 11A PS
| EIA type | Vaccine | Vaccinees | No. of serum specimens available | Specimens collected at: |
|---|---|---|---|---|
| Inhibition | PS | Adults | 11 | d0,a d28b |
| PncD | Adults | 12 | d0,a d28b | |
| PncD at 2, 4, and 6 mo | Infants | 24 | 7 mo | |
| None | Infants | 49 | 6, 7, 14 moc | |
| Specific for IgG to 11A PS | PncD at 2, 4, and 6 mo; PncD at 14 mo | Infants | 12 | 14 mo (pre), 15 mo (post) |
| PncD at 2, 4, and 6 mo; PS at 14 mo | Infants | 11 | 14 mo (pre), 15 mo (post) | |
| PncD/T conjugate | Adults | 11 | d0, d28 | |
| PS | Adults | 10 | d0, d28 | |
| PRP-D/PRP-D and MenACYW | Adults | 12 | d0, d28 |
a
d0, day zero (adult preimmunization sera).
b
d28, day 28 (adult postvaccination sera).
c
Referred to as sera from nonimmunized infants.