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. 2022 Oct 14;46(1):165–174. doi: 10.1038/s41440-022-01077-x

Table 1.

Demographics, blood pressure profiles, treatments and outcomes of patients

Controlled Hypertension
(n = 115)
Uncontrolled Hypertension
(n = 236)
P value Non-Severe Covid-19
(n = 137)
Severe covid-19
(n = 214)
P value
Demographics
  Age, year 52 ± 17 55 ± 26 0.473 50 ± 27 56 ± 30 0.053
  Sex, men 41.2% 58.8% 0.033 51.2% 49.9% 0.231
BP on admission
  SBP, mmHg 126 ± 18 144 ± 31 0.007 128 ± 10 130 ± 22 0.144
  DBP, mmHg 81 ± 11 92 ± 18 0.043 80 ± 9 80 ± 15 0.556
  MAP, mmHg 96 ± 13 97 ± 16 0.632 99 ± 20 97 ± 23 0.473
Comobidities
  Diabetes mellitus 32.9% 25.6% 0.063 14.6% 34.5% 0.003
  CAD 32.9% 17.6% 0.556 32.9% 27.6% 0.556
  CKD 14.1% 33.3% 0.188 14.1% 33.3% 0.188
  Heart failure 10.6% 17.6% 0.631 10.6% 17.6% 0.631
Antihypertensive drugs on admission
  AdCEis/ARBs 60.5% 64.2% 0.152 60% 62.3% 0.209
  Beta blockers 18.5% 25% 0.131 25.2% 22.3% 0.440
  CCBs 42% 43.1% 0.665 44.5% 46.8% 0.556
  Diuretics 22.3% 19.3% 0.154 23.1% 18,3% 0.188
  Any of drugs above 12.3% 27.9% 0.045 33.4% 27% 0.052
Other medications
  Glucocorticoid 86.9% 83.8% 0.822 87.5% 92.5% 0.082
  Anticoagulant 52.1% 55.1% 0.898 36.49% 84.1% 0.000
BP Profile during hospitalization
  MAPCV 2.1 ± 2.85 3.27 ± 4.9 0.002 2.9 ± 3.77 1.88 ± 2.42 0.000
  High BPV 40.2% 59.8% 0.003 68.4% 31.6% 0.005
Outcome
  In-hospital mortality 16.52% 46.08% 0.003 8.02% 37.8% 0.000

ABP blood pressure, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, CAD coronary artery disease, CKD chronic kidney disease, ACEis angiotensin converting enzyme inhibitors, ARBs angiotensin receptor blockers, CCBs calcium channel blockers, MAPCV mean arterial pressure coefficient of variation, BPV blood pressure variability