Table 1.
Controlled Hypertension (n = 115) |
Uncontrolled Hypertension (n = 236) |
P value | Non-Severe Covid-19 (n = 137) |
Severe covid-19 (n = 214) |
P value | |
---|---|---|---|---|---|---|
Demographics | ||||||
Age, year | 52 ± 17 | 55 ± 26 | 0.473 | 50 ± 27 | 56 ± 30 | 0.053 |
Sex, men | 41.2% | 58.8% | 0.033 | 51.2% | 49.9% | 0.231 |
BP on admission | ||||||
SBP, mmHg | 126 ± 18 | 144 ± 31 | 0.007 | 128 ± 10 | 130 ± 22 | 0.144 |
DBP, mmHg | 81 ± 11 | 92 ± 18 | 0.043 | 80 ± 9 | 80 ± 15 | 0.556 |
MAP, mmHg | 96 ± 13 | 97 ± 16 | 0.632 | 99 ± 20 | 97 ± 23 | 0.473 |
Comobidities | ||||||
Diabetes mellitus | 32.9% | 25.6% | 0.063 | 14.6% | 34.5% | 0.003 |
CAD | 32.9% | 17.6% | 0.556 | 32.9% | 27.6% | 0.556 |
CKD | 14.1% | 33.3% | 0.188 | 14.1% | 33.3% | 0.188 |
Heart failure | 10.6% | 17.6% | 0.631 | 10.6% | 17.6% | 0.631 |
Antihypertensive drugs on admission | ||||||
AdCEis/ARBs | 60.5% | 64.2% | 0.152 | 60% | 62.3% | 0.209 |
Beta blockers | 18.5% | 25% | 0.131 | 25.2% | 22.3% | 0.440 |
CCBs | 42% | 43.1% | 0.665 | 44.5% | 46.8% | 0.556 |
Diuretics | 22.3% | 19.3% | 0.154 | 23.1% | 18,3% | 0.188 |
Any of drugs above | 12.3% | 27.9% | 0.045 | 33.4% | 27% | 0.052 |
Other medications | ||||||
Glucocorticoid | 86.9% | 83.8% | 0.822 | 87.5% | 92.5% | 0.082 |
Anticoagulant | 52.1% | 55.1% | 0.898 | 36.49% | 84.1% | 0.000 |
BP Profile during hospitalization | ||||||
MAPCV | 2.1 ± 2.85 | 3.27 ± 4.9 | 0.002 | 2.9 ± 3.77 | 1.88 ± 2.42 | 0.000 |
High BPV | 40.2% | 59.8% | 0.003 | 68.4% | 31.6% | 0.005 |
Outcome | ||||||
In-hospital mortality | 16.52% | 46.08% | 0.003 | 8.02% | 37.8% | 0.000 |
ABP blood pressure, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, CAD coronary artery disease, CKD chronic kidney disease, ACEis angiotensin converting enzyme inhibitors, ARBs angiotensin receptor blockers, CCBs calcium channel blockers, MAPCV mean arterial pressure coefficient of variation, BPV blood pressure variability