Table 2.
Summary baseline lung function grading data, cardiovascular disease, and subsequent survival data for 1165 patients seen at specialist respiratory outreach clinics
| Normal (Z ≥ − 1.64) | Abnormal (Z < − 1.64) | |||
|---|---|---|---|---|
| Mild (Z − 1.64 to − 3) | Moderate (Z − 3 to − 5) | Severe (Z < − 5) | ||
| DLCO | ||||
| n (%) | 697 (60) | 270 (23) | 147 (13) | 51 (4) |
| CVD (%) | 103/697 (15) | 57/270 (21) | 64/147 (44) | 17/51 (33) |
| Deaths (%) | 24/697 (3) | 24/270 (9) | 37/147 (25) | 23/51 (45) |
| KCO | ||||
| n (%) | 901 (77) | 149 (13) | 97 (8) | 18 (2) |
| CVD (%) | 157/901 (17) | 41/149 (28) | 39/97 (40) | 4/18 (22) |
| Deaths (%) | 49/901 (5) | 19/149 (13) | 29/97 (30) | 11/18 (61) |
| VA | ||||
| n (%) | 753 (65) | 324 (28) | 84 (7) | 4 (< 1) |
| CVD (%) | 121/753 (23) | 90/324 (28) | 29/84 (35) | 1/4 (25) |
| Deaths (%) | 53/753 (7) | 37/324 (11) | 17/84 (20) | 1/4 (25) |
| FEV1 | ||||
| n (%) | 590 (51) | 364 (31) | 200 (17) | 11 (1) |
| CVD (%) | 96/590 (16) | 87/364 (24) | 55/300 (28) | 3/11 (27) |
| Deaths (%) | 30/590 (5) | 33/364 (9) | 43/200 (22) | 2/11 (18) |
| FVC | ||||
| n (%) | 708 (61) | 341 (29) | 111 (10) | 5 (< 1) |
| CVD (%) | 115/708 (16) | 90/341 (26) | 35/111 (32) | 1/5 (20) |
| Deaths (%) | 40/708 (6) | 41/341 (12) | 26/111 (23) | 1/5 (20) |
| FEV1/FVC | ||||
| n (%) | 802 (69) | 199 (17) | 151 (13) | 13 (1) |
| CVD (%) | 158/802 (20) | 42/199 (21) | 40/151 (26) | 1/13 (8) |
| Deaths (%) | 60/802 (7) | 19/199 (10) | 26/151 (17) | 3/13 (23) |
CVD, cardiovascular disease; DLCO, diffusing capacity of the lung for carbon monoxide; KCO, transfer coefficient of the lung for carbon monoxide; VA, alveolar volume