Table 3.
Results for NBS for CAH in New Zealand (2018–2021) (Protocol 1) compared with modelling for Protocol 2. NICU: Neonatal Intensive Care Unit.
| Protocol 1 | Protocol 2 | |
|---|---|---|
| No Second Tier Tests | ||
| BW ≤ 1500 g NICU | 1149 | 652 |
| BW ≥ 1500 g NICU | 765 | 765 |
| Community or Birthing Units | 489 | 489 |
| Positive Tests | ||
| BW ≤ 1500 g NICU | 36 | 3 |
| BW ≥ 1500 g NICU | 48 | 12 |
| Community or Birthing Units | 25 | 9 |
| False Positive Tests | ||
| BW ≤ 1500 g NICU | 36 | 3 |
| BW ≥ 1500 g NICU | 45 | 9 |
| Community or Birthing Units | 17 | 1 |
| Total FP Tests | 98 | 13 |
| Screening Specificity | 99.96% | >99.99% |
| Chi Squared Test | X2 = 53.0324, p < 0.0001 | |
| Retrospective and Prospective Confirmed CAH NBS Specimens | ||
| Number of Specimens | 46 | |
| Positive Test Results | 36 | 40 |
| Sensitivity | 78% | 87% |
| Chi Squared Test | X2 = 2.24, p = 0.1338 | |