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Soluble CD146 induces U87 cell proliferation, migration and invasion and promotes CSC/EMT markers. U87 cells were treated with 100 ng/ml of VEGF, rsCD146 or combination of both molecules for 48 h and cell proliferation (a), migration (b) and invasion (c) were determined. EMT (d) and CSC (e) markers were also examined after 48 h of treatment with 100 ng/ml sCD146. Representative blots from 5 experiments are shown. *p < 0.05, **p < 0.01, ***p < 0.001, experimental vs control
