| Study period | |||||
|---|---|---|---|---|---|
| Enrollment | Allocation | Post allocation | |||
| Timepoint | − T1 | T0 | T1 (intervention) | T2 (8-month follow up) | T3 (14-month follow up) |
| Patients visits | x | ||||
| Eligibility screen | x | ||||
| Informed consent | x | ||||
| Randomization: split-mouth | x | ||||
| Intervention | |||||
| Tomography (T1, T2, and T3) | x | x | x | ||
| Graft installation | x | ||||
| Implant placement and biopsies | x | ||||
| Healing caps placement | x | ||||
| Assessments | |||||
| Surgery analysis | x | ||||
| Implant stability | x | x | |||
| Biopsies | x | ||||
| Biopsies analyses | x | x | |||
| Adverse events | x | x | x | ||
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