Table 1.

Summary of scATAC-seq experiments with different sample preparation and preservation protocols

Sample preservation	Sample preparation	Tissues	Reference
Fresh	Cell	Cell line, PBMC	(Buenrostro et al. 2015; Mezger et al. 2018)
Fresh	Nuclei	Cell line, PBMC, human cortex, Arabidopsis thaliana, fly	(Cusanovich et al. 2015; Satpathy et al. 2019; Dorrity et al. 2021; Mich et al. 2021; Janssens et al. 2022)
Frozen	Cell	Cell line, human and mouse skin fibroblast, mouse cardiac progenitor cells, mouse splenocytes	(Chen et al. 2018b)
Frozen	Nuclei	Mouse brain, 30 adult human tissues	(Lareau et al. 2019; Zhang et al. 2021b)
Frozen	Fixed nuclei	15 human fetal tissues	(Domcke et al. 2020)