Table 4.
Summary of computational methods for candidate protein prioritization with respect to a particular function
| Method | Mode | Downstream | Network | Technique |
|---|---|---|---|---|
| Mashup (Cho et al. 2016) | Unsupervised | SVM | Multiple | Traditional |
| deepNF (Gligorijevic et al. 2018) | Unsupervised | SVM | Multiple | Deep learning |
| DeepMNE-SVM (Xue et al. 2019) | Unsupervised | SVM | Multiple | Deep learning |
| DeepMNE-CNN (Peng et al. 2021) | Unsupervised | CNN | Multiple | Deep learning |
| BIONIC (Forster et al. 2021) | Unsupervised | LR | Multiple | Deep learning |
| RANKS (Valentini et al. 2016) | Semi-supervised | – | Single | Traditional |
| GeneMANIA (Mostafavi et al. 2008; Mostafavi and Morris 2010) | Semi-supervised | – | Multiple | Traditional |