Table 1.
Comparisons of distributions of NPFFR1 and NPFFR2 mRNA in human and rat tissues.4
| Tissue | hNPFFR1 | hNPFFR2 | rNPFFR1 | rNPFFR2 |
|---|---|---|---|---|
| Amygdala | 44% | 27% | 57% | 42% |
| Cerebellum | 20% | Trace | 17% | 10% |
| Heart | Trace | Trace | 3% | 82% |
| Hippocampus | 45% | 7% | 20% | 8% |
| Hypothalamus | 21% | 2% | 100% | 84% |
| Kidney | 1% | 1% | 1% | 20% |
| Liver | Trace | Trace | 2% | 3% |
| Lung | 7% | 1% | 4% | 16% |
| Pancreas | Trace | 1% | Trace | Trace |
| Pituitary | 2% | 5% | 24% | 34% |
| Placenta | Trace | 100% | N/A | N/A |
| Spinal cord | 100% | 1% | 24% | 100% |
| Spleen | 8% | 4% | Trace | Trace |
| Stomach | 1% | Trace | Trace | 14% |
| Skeletal muscle | 1% | 1% | Trace | Trace |
| Substantia nigra | 13% | 1% | 49% | 67% |
| Thalamus | 30% | 2% | 3% | 15% |
| Whole brain | 21% | 8% | 21% | 24% |
Note: mRNA levels are expressed as percent of highest expressing tissue: spinal cord for hNPFFR1, placenta for hNPFFR2, hypothalamus for rNPFFR1 and spinal cord for rNPFFR2. N/A: Not Available.