. Author manuscript; available in PMC: 2022 Oct 24.

Published in final edited form as: Toxicol In Vitro. 2022 Jan 13;80:105313. doi: 10.1016/j.tiv.2022.105313

Table 3.

Effect of Ascorbic Acid by Chemical Classification and Reactivity

Classification	Number	OS I		OS II		P-valule¹	OS II - OS I		P-value²
Classification	Number	Avg.OD	SE	Avg. OD	SE	P-valule¹	Avg. ΔOD	SE	P-value²
True Negative
Non Reactive	13	307.2	16.9	300.1	14.5	NS	−7.1	14.5	NS
Reactive	5	299.9	18.0	295.1	11.0	NS	−4.8	6.0	NS
False Positives
Non Reactive	8	1044.8	266.2	938.6	277.4	NS	−105.8	14.1	<0.05
Reactive	10	1009.5	251.6	411.8	57.4	<0.05	−597.7	76.9	<0.05
True Positives
Non Reactive	21	1452.1	136.0	1318.0	124.2	NS	−134.1	40.8	NS
Reactive	5	1450.5	252.3	1456.3	300.5	NS	5.8	134.8	NS

Table 3. OS I = OptiSafe without Ascorbic acid; OS II = OptiSafe with Ascorbic acid; Avg. OD = Average optical density value; SE = Standard error; Avg. ΔOD = Average change in OD value;

^{1 =}

Effects of ascorbic acid on measured OD of chemicals;

^{2 =}

Comparison of the effects of ascorbic acid on non-reactive versus reactive chemicals;

NS = Not significant.