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. Author manuscript; available in PMC: 2022 Oct 24.
Published in final edited form as: NMR Biomed. 2017 Sep 29;30(12):10.1002/nbm.3796. doi: 10.1002/nbm.3796
Benign vs. All Cancer

Modalities Parameters AUC Sensitivity Specificity
T2w, DWI ADC 0.94 89.2 84.5
T2w, DCE T2,Slope, kep 0.90 86.2 81.0
T2w, MRSI Cho/Cre 0.99 98.5 84.8
T2, DWI, DCE Slope, vl, ADC 0.96 90.8 89.7
T2, DCE, MRSI Slope, Cho/Cre, CCC, vl, T2, Cho/Cit 1.00 100 100
T2, DWI, MRSI ADC, Cho/Cre 1.00 98.5 98.3

All Cho/Cre, ADC 1.0 98.5 98.3

≤G3+3 vs. ≥G3+4
Modalities Parameters AUC Sensitivity Specificity
T2w, DWI ADC 0.69 76.6 61.3
T2w, DCE Slope 0.65 57.5 74.2
T2w, MRSI Cho, Cho/Cre 0.76 68.1 83.9
T2, DWI, DCE ADC, Slope 0.73 63.8 77.4
T2, DCE, MRSI Cho, Slope, Cit 0.80 63.8 87.1
T2, DWI, MRSI Cho, ADC, Cit 0.79 78.7 74.2

All Cho, ADC, Kep, Cit 0.83 76.6 80.6

≤G3+4 vs. ≥G4+3
Modalities Parameters AUC Sensitivity Specificity
T2w, DWI ADC 0.67 54.3 80.8
T2w, DCE WO 0.62 60.0 70.2
T2w, MRSI Cre, Cho 0.77 80.0 66.0
T2, DWI, DCE ADC, WO 0.69 48.6 87.2
T2, DCE, MRSI Cre, Cho, WO 0.81 71.4 78.7
T2, DWI, MRSI Cre, Cho, ADC 0.80 82.9 66.0

All Cre, Cho, WO 0.81 71.4 78.7

Slope = maximal enhancement slope, WO = washout slope