FIGURE 1.

Specific reasons for which the antimicrobial prescriptions were evaluated as inappropriate per study year. Inappropriate prescriptions were sub-classified into “unnecessary” (UNN), “inadequate” drug (INA) according to susceptibility testing or lack of coverage for the main etiological pathogens for the specific syndrome, “adequate but not recommended” (ANR) if the drug chosen was adequate considering the spectrum, dose, route and duration but it was not the first option recommended by the guideline without any reason for not using the first option (this was considered a marker of the guideline adherence), “inadequate dose” (IDOS), “inadequate route” (IROU) and “inadequate duration” (IDUR).