Figure 6.

MiR-452-5p facilitated BC cells survival by downregulating RGS2. MDA-MB-231 and HCC1937 were transfected with an empty vector, mimic-NC, RGS2-OE (OE), mimic, or OE+mimic. (a) Cell viability in BC cells transfected as described above was uncovered utilizing CCK-8 assay. (b) Bax and Bcl-2 protein levels were uncovered utilizing western blotting analysis in BC cells transfected as described above. (c) Migrated cells were counted utilizing transwell in BC cells transfected as described above. ^∗P < 0.05; ^∗∗P < 0.001 vs empty vector; ^∗P < 0.05, ^^P < 0.001 vs mimic-NC; #P < 0.05, ##P < 0.001 vs OE+mimic.