Table 1.
Comparing Risk Factors and Demographic Data of Patients Who Filled Additional Opioid Prescriptions With Those Who Did Not, and of Patients With Prolonged Postoperative Opioid Use With Those Who Did Not
| Total N = 634 |
Zero Refills N = 443 |
≥1 Opioid Refill N = 191 |
P Value | No Prolonged Use N = 545 |
Prolonged 3-6 mo Use N = 89 |
P Value | |
| Age (yr) | 59.4 (14.7) | 59.2 (15.1) | 59.9 (13.6) | 0.735 | 59.2 (14.7) | 60.6 (14.7) | 0.452 |
| Sex | 0.772 | 0.324 | |||||
| Female | 438 (69.1%) | 304 (68.6%) | 134 (70.2%) | 381 (69.9%) | 57 (64.0%) | ||
| Male | 196 (30.9%) | 139 (31.4%) | 57 (29.8%) | 164 (30.1%) | 32 (36.0%) | ||
| Preoperative opioid use | <0.001 | <0.001 | |||||
| No | 453 (71.5%) | 355 (80.1%) | 98 (51.3%) | 423 (77.6%) | 30 (33.7%) | ||
| Yes | 181 (28.5%) | 88 (19.9%) | 93 (48.7%) | 122 (22.4%) | 59 (66.3%) | ||
| Initial postoperative opioid prescription | |||||||
| Daily dose ≥ 50 MMEs | 0.615 | 0.571 | |||||
| No | 517 (81.5%) | 364 (82.2%) | 153 (80.1%) | 442 (81.1%) | 75 (84.3%) | ||
| Yes | 117 (18.5%) | 79 (17.8%) | 38 (19.9%) | 103 (18.9%) | 14 (15.7%) | ||
| >7 Day duration | 0.026 | <0.001 | |||||
| No | 604 (95.3%) | 428 (96.6%) | 176 (92.1%) | 528 (96.9%) | 76 (85.4%) | ||
| Yes | 30 (4.73%) | 15 (3.39%) | 15 (7.85%) | 17 (3.12%) | 13 (14.6%) | ||
| Overlapping opioid prescriptions | <0.001 | <0.001 | |||||
| No | 594 (93.7%) | 431 (97.3%) | 163 (85.3%) | 528 (96.9%) | 66 (74.2%) | ||
| Yes | 40 (6.31%) | 12 (2.71%) | 28 (14.7%) | 17 (3.12%) | 23 (25.8%) | ||
| Total MME/prescription | 139 (137) | 122.6 (77.3) | 177.0 (215.2) | 0.002 | 128.7 (81.3) | 202.1 (298.2) | 0.318 |
| Duration (d) | 4.25 (3.97) | 3.9 (2.9) | 5.1 (5.7) | 0.009 | 3.9 (2.7) | 6.4 (7.9) | 0.026 |
| Quantity of pills | 21.6 (14.3) | 19.7 (9.6) | 25.9 (21.1) | 0.001 | 20.6 (10.5) | 27.4 (27.5) | 0.277 |
MME = milligram morphine equivalent