Table 3.

Multivariate Cox-proportional hazard analysis of 2-year events after propensity-score matching.

	Beta-blockers (N = 1048)				RASI (N = 1559)
Events	With BB (N = 685)	Without BB (N = 363)	Hazard ratio* (95% CI)	P value	With RASI (N = 1003)	Without RASI (N = 556)	Hazard ratio* (95% CI)	P value
MACE	103 (8.7)	73 (12.8)	0.68 (0.50-0.93)	.015	151 (8.9)	89 (9.6)	0.95 (0.73-1.23)	.676
Cardiac death	32 (2.5)	25 (4.0)	0.67 (0.38-1.16)	.154	42 (2.3)	27 (2.7)	0.91 (0.55-1.49)	.700
All-cause death	54 (4.3)	38 (6.1)	0.69 (0.45-1.05)	.085	75 (4.1)	45 (4.5)	0.96 (0.66-1.39)	.809
MI	20 (1.6)	19 (3.1)	0.50 (0.26-0.95)	.035	28 (1.6)	18 (1.8)	0.91 (0.50-1.67)	.763
Revascularization	50 (4.1)	38 (6.5)	0.62 (0.41-0.95)	.030	83 (4.8)	39 (4.0)	1.22 (0.83-1.79)	.306
Heart failure†	29 (2.4)	14 (2.3)	1.06 (0.55-2.03)	.868	33 (1.8)	34 (3.5)	0.53 (0.33-0.86)	.010
Stroke	12 (1.0)	9 (1.4)	0.69 (0.29-1.66)	.409	15 (0.8)	12 (1.2)	0.72 (0.33-1.55)	.395
MACCE	111 (9.5)	78 (13.7)	0.70 (0.52-0.94)	.017	163 (9.7)	98 (10.6)	0.92 (0.71-1.18)	.514
MACE with NCD	124 (10.5)	82 (14.3)	0.72 (0.54-0.96)	.025	182 (10.7)	102 (11.0)	0.99 (0.78-1.27)	.954

Values are number of patients with events (rate per 100 patient-years).

BB = beta-blockers, CI = confidence interval, MACCE = major adverse cardiac and cerebrovascular event, MACE = major adverse cardiac event, MI = myocardial infarction, NCD = Non-cardiac death, RASI = inhibitors of renin-angiotensin system.

^*Adjusted for age, sex, body mass index, hypertension, diabetes mellitus, prior angina, prior MI, prior heart failure, current smoker, Killip class, estimated glomerular filtration rate, left ventricular ejection fraction, type of myocardial infarction, coronary reperfusion, and medications (aspirin, P2Y12 inhibitors, beta-blockers or RASI, and statins) at discharge.

^†Re-hospitalization due to heart failure.