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. 2022 Oct 19;16:2845–2865. doi: 10.2147/PPA.S379197

Table 3.

Rheumatoid Arthritis-Related Information with Univariate Analysis and Resulting p values for Differences Between Activation Levels

Patient Activation Level Level 1 Level 2 Level 3 Level 4 Total p value
Seropositivity (%)
Positive 9 (11.0) 15 (18.3) 32 (39.0) 26 (31.7) 82 (68.9) 0.399
Erythrocyte sedimentation Rate (standard deviation) 32 (28) 39 (30) 31 (30) 27 (23) 31 (28) 0.339
Disease duration, years 11.4 (6.6) 13.4 (8.8) 14.9 (7.1) 12.8 (8.3) 13.5 (7.8) 0.198
Disease duration (%)
 Early (≤2 years) 2 (33.3) 1 (16.7) 1 (16.7) 2 (33.3) 6 (3.1) 0.466
 Established (>2 years) 24 (12.7) 26 (13.8) 69 (36.5) 70 (37.0) 189 (96.9)
Disease activity score - erythrocyte sedimentation rate (%)
 DAS28-ESR median (IQR) 1.21 (0.00–2.46) 2.41 (0.00–3.18) 0.68 (0.00–3.03) 0.87 (0.00–2.64) 1.14 (0.00–2.46) 0.822
 Remission to mild 19 (15.1) 18 (14.3) 42 (33.3) 47 (37.3) 126 (69.6) 0.271
 Moderate to severe 4 (7.3) 9 (16.4) 25 (45.5) 17 (30.9) 55 (30.4)
csDMARDs 11 (11.1) 17 (17.2) 33 (33.3) 38 (38.4) 99 (50.3) 0.346
TNFi, non-TNFi, small molecule agents 8 (9.4) 16 (18.8) 33 (38.8) 28 (32.9) 85 (43.1) 0.126
Corticosteroids (%) 1 (3.4) 5 (17.2) 12 (41.4) 11 (37.9) 29 (14.7) 0.361
NSAIDs (%) 0 (0.0) 3 (27.3) 4 (36.4) 4 (36.4) 11 (5.6) 0.367

Note: *Significance level according to p < 0.05.