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. 2022 Oct 11;12:1028899. doi: 10.3389/fcimb.2022.1028899

Figure 2.

Figure 2

Pre-exposure to S. japonicum eggs upregulated Treg immune response in the TNBS-induced experimental colitis. (A, B) The proportion of CD25+Foxp3+Treg in CD4+ T cells in spleen. (C) The mRNA expression level of Foxp3. The concentrations of IL-10 and TGF-β1 in serum (D, E, respectively) and in splenic supernatants (F, G, respectively). Data are expressed as means ± SEMs based on 6 mice in each group and from 2 independent experiments. Asterisks mark significant differences among different groups (**P < 0.01, ***P < 0.001).