TABLE 3.
Patient characteristics after 1:1 propensity score matching.
| Variable | Total | Tigecycline | Imipenem–cilastatin | p value |
|---|---|---|---|---|
| (n = 426) | (n = 213) | (n = 213) | ||
| Age (years) | 58.5 (39.0–69.0) | 54.0 (37.0–69.0) | 61.0 (45.0–70.0) | 0.196 |
| Sex, female (%) | 134 (31.5%) | 70 (32.9%) | 64 (30.0%) | 0.531 |
| ICU admission (%) | 200 (46.9%) | 96 (45.1%) | 104 (48.8%) | 0.437 |
| Comorbidities (%) | ||||
| Diabetes mellitus | 55 (12.9%) | 32 (15.0%) | 23 (10.8%) | 0.193 |
| Hypertension | 108 (25.4%) | 60 (28.2%) | 48 (22.5%) | 0.181 |
| Chronic heart failure | 16 (3.8%) | 9 (4.2%) | 7 (3.3%) | 0.610 |
| Atrial fibrillation | 3 (0.7%) | 0 (0.0%) | 3 (1.4%) | 0.248 |
| Chronic obstructive pulmonary disease | 9 (2.1%) | 4 (1.9%) | 5 (2.3%) | 1.000 |
| Chronic kidney disease | 49 (11.5%) | 27 (12.7%) | 22 (10.3%) | 0.448 |
| Chronic liver disease | 66 (15.5%) | 34 (16.0%) | 32 (15.0%) | 0.789 |
| Malignancy | 170 (39.9%) | 86 (40.4%) | 84 (39.4%) | 0.843 |
| Shock | 123 (28.9%) | 62 (29.1%) | 61 (28.6%) | 0.915 |
| Type of infection (%) | 0.072 | |||
| Pneumonia | 247 (58.0%) | 126 (59.2%) | 121 (56.8%) | |
| Intra-abdominal infection | 109 (25.6%) | 45 (21.1%) | 64 (30.0%) | |
| Bloodstream infection | 48 (11.3%) | 26 (12.2%) | 22 (10.3%) | |
| Skin and soft tissue infection | 16 (3.8%) | 11 (5.2%) | 5 (2.3%) | |
| Others | 6 (1.4%) | 5 (2.3%) | 1 (0.5%) | |
| Incidence of GNB isolated (%) | 234 (54.9%) | 115 (54.0%) | 119 (55.9%) | 0.697 |
| Mechanical ventilation (%) | 155 (36.4%) | 78 (36.6%) | 77 (36.2%) | 0.920 |
| CRRT (%) | 54 (12.7%) | 26 (12.2%) | 28 (13.1%) | 0.771 |
| Duration of administering antibiotics (days) | 9.0 (7.0–14.0) | 9.0 (8.0–13.0) | 9.0 (6.0–14.0) | 0.356 |
Data are expressed as medians (interquartile range), or number (percentage).