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. 2022 Oct 4;25(11):105270. doi: 10.1016/j.isci.2022.105270

Figure 6.

Figure 6

TM7SF3 modulates the activity of HNRNPK

(A) Voila analysis of RNAseq data of genes whose expression is not affected by siTM7SF3.

(B–E) U2-OS cells were transfected with indicated siRNAs or with a non-targeting sequence. RNA was extracted, and splicing variants of the indicated genes ADD3 (B), CLSTN1(C), PLEKHM2 (D), and ECHDC1 (E) were determined by PCR. Bar graphs represent the mean percentage of the spliced-out exons shown in each scheme (NonT = 100%) as measured by PCR products densitometry in 4 independent experiments Results are presented as means ± SEM (∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001).