REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse monoclonal anti-hnRNPK	Santa Cruz Biotechnology	Cat#: sc-28380 RRID:AB_627734
Mouse anti-IgG2B	Santa Cruz Biotechnology	Cat#: sc-3879 RRID:AB_737262
Mouse monoclonal anti-hnRNPU	Millipore	Cat#: 05-1516 RRID:AB_10563506
Mouse monoclonal anti-GAPDH	Millipore	Cat# MAB374 RRID:AB_2107445
Rabbit polyclonal anti-H2B	Millipore	Cat#07371 RRID:AB_310561
Rabbit polyclonal anti-HSP90	Cell Signaling Technology	Cat#: 4874 RRID: AB_2121214
Mouse monoclonal anti-Y14	Abcam	Cat# ab5828 RRID:AB_2269494
Rabbit polyclonal anti-U2AF65	Abcam	Cat# ab37530 RRID:AB_883336
Mouse monoclonal anti-PI(4,5)P2	Echelon biosciences	Cat#Z-P045 RRID:AB_427225
Rabbit polyclonal anti-SF1	Antibody Verify	N/A
Rabbit polyclonal anti-RBM14	Antibody Verify	N/A
Guinea Pig polyclonal anti-Insulin	DAKO	Cat#: A0564 N/A
Mouse monoclonal anti-SRSF2	Sigma	Cat# S4045 RRID:AB_477511
Rabbit polyclonal anti-TM7SF3 N-terminus	Sigma	Cat# HPA057640 N/A
Rabbit polyclonal anti-TM7SF3 C-Terminus	Sigma, This paper	N/A
Mouse monoclonal anti-α1-subunit of Na+/K+-ATPase (6H)	Dr. M. J. Caplan, Yale	N/A
Oligonucleotides
Primers for qPCR and PCR, see Tables S2 and S3	This paper	N/A
siRNA-human TM7SF3	Horizon Discovery	Cat# M-005745-00-0010
Human siCON	Horizon Discovery	Cat# D-OO1206-13-20
siRNA-Human hnRNPK	Horizon Discovery	Cat# M-011692-00-0005
Chemicals, peptides, and recombinant proteins
Protein A-agarose beads	Santa Cruz	Cat# sc-2001
Blocking peptide - IKELFQKEQPAGERTPL	Sigma	Customized N/A
Actinomycin D	Sigma	Cat# A1410
High-capacity cDNA reverse transcription kit	ThermoFisher Scientific	Cat# 4368813
Lipofectamine 2000 reagent	ThermoFisher Scientific	Cat# 13778-075
SYBR Green Master Mix	ThermoFisher Scientific	Cat# A25743
Experimental models: Cell line
U2-OS	ATCC	Cat# HTB-96
HepG2	ATCC	Cat# HB-8065
HFF	ATCC	Cat# SCRC-1041
Software and algorithms
ImageJ	NIH	https://imagej.nih.gov/ij/
Prism	Graphpad	https://www.graphpad.com/scientificsoftware/prism/
Image Lab	BioRad	https://www.bio-rad.com/en-us/product/chemidoc-xrs-system?ID=NINJHRKG4
STRING analysis	Szklarczyk et al., 2015) PMID:25352553	https://string-db.org/
AlphaFold2	Jumper et al. (2021) {PMID: 34265844}	AlphaFold2.ipynb - Colaboratory (google.com)