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. 2022 Oct 18;8(10):e11154. doi: 10.1016/j.heliyon.2022.e11154

Table 3.

ddCts and percentage of the ace, esp, asa1, and efaA transcripts levels in penicillin-resistant, ampicillin-susceptible Enterococcus faecalis (PRASEF), and penicillin- and ampicillin-susceptible E. faecalis (PSASEF) exposed to sub-minimal inhibitory concentrations of gentamicin or ampicillin.

Transcript Antibiotics ddCT PRASEF (Treated–Non-treated)
ddCT PSASEF (Treated–Non-treated)
Mean ± SD (%) P-value Mean ± SD (%) P-value
ace Gentamicin +0.16 ± 1.86 (−11.73%) 0.874 −0.12 ± 1.13 (+7.98%) 0.842
Ampicillin +1.06 ± 1.33 (−108.49%) 0.210 +2.17 ± 1.01 (−350.02%) 0.023
esp Gentamicin +0.05 ± 1.72 (−3.81%) 0.948 +0.43 ± 0.83 (−34.72%) 0.376
Ampicillin −0.51 ± 1.37 (−42.41%) 0.448 −0.12 ± 2.48 (+7.98%) 0.929
asa1 Gentamicin +0.37 ± 1.40 (−29.24%) 0.636 +1.60 ± 1.53 (−203.14%) 0.128
Ampicillin +1.16 ± 1.40 (−123.46%) 0.198 +2.82 ± 0.90 (−606.16%) 0.008
efaA Gentamicin −1.37 ± 1.84 (+61.31%) 0.170 −0.90 ± 0.75 (+46.41%) 0.098
Ampicillin −0.37 ± 1.96 (+22.62%) 0.695 −0.96 ± 1.10 (+48.59%) 0.177

ddCt was determined considering the means of standardized Cts for PRASEF and PSASEF according to the absence or presence of antibiotics.

%, percentage of increase (+) or decrease (−) in the transcript level calculated from the ddCt.

SD, Standard Deviation.