Table I.
Subject | Diagnosis | Sex | Age, years | Time elapsed from diagnosis, years | Anti-inflammatory medication | ANAAb | ENAAb | CLASI |
---|---|---|---|---|---|---|---|---|
1 | DLE | Male | 30 | 2 | HCQ | Negative | Negative | 6 |
2 | DLE | Female | 51 | 12 | mepacrine | Negative | RNP | 9 |
3 | DLE | Male | 53 | 11 | None | Negative | Negative | 10 |
4 | DLE | Female | 56 | >25 | None | Negative | SSB | 18 |
5 | DLE | Female | 59 | 0 | HCQ + MTX | Negative | SSA | 21 |
6 | DLE | Female | 63 | 2 | NONE | Positive | ND | 5 |
7 | DLE | Female | 64 | 1 | MTX | Negative | Positive | 9 |
8 | DLE | Female | 80 | 7 | HCQ | Negative | Negative | 5 |
9 | SCLE | Female | 57 | 0 | NONE | Negative | SSA | 9 |
10 | SCLE | Male | 59 | 1 | PRED | Negative | SSA | 12 |
11 | SCLE | Female | 62 | 4 | HCQ | Positive | SSA, SSB | 8 |
12 | SCLE | Female | 67 | 0 | PRED + etanercept | Positive | SSA | 18 |
13 | SCLE | Female | 67 | 0 | None | Negative | SSA | 10 |
14 | SCLE | Female | 74 | 3 | HCQ | Positive | SSA | 7 |
15 | SCLE | Female | 83 | 0 | None | Positive | SSA, SSB | 8 |
16 | SLE | Female | 19 | 12 | HCQ + PRED | Positive | SSA, SSB | 4 |
17 | SLE | Female | 40 | 26 | HCQ + MTX + PRED | Positive | SSA, SSB | 16 |
18 | SLE | Female | 46 | 30 | HCQ + MTX + PRED + infliximab | Positive | RNP | 14 |
19 | SLE | Female | 56 | 10 | HCQ + PRED + rituximab | Positive | SSA, SSB | 16 |
20 | SLE | Female | 69 | 25 | HCQ + PRED | Positive | SSA | 5 |
Medication dosages at the time of sampling: hydroxychloroquine 100–400 mg/day, mepacrine 100 mg/day, methotrexate 7.5–20 mg/week, prednisolone: 60 mg/day (patient 10), 20 mg/day (patient 12), 5 mg every other day (patient 16), 5 mg/day (patient 17), 5 mg/day (patient 18), 45 mg/day (patient 19) and 10 mg/day (patient 20). DLE: discoid lupus erythematosus; SCLE: subacute cutaneous lupus erythematosus; SLE: systemic lupus erythematosus; HCQ: hydroxychloroquine; MTX: methotrexate; PRED: prednisolone; ANAAb: anti-nuclear antibody; ENAAb: extractable nuclear antibodies; RNP: ribonucleoprotein; SSA: anti-Ro; SSB: anti-La.