Table 2.

Performances of the optimized SVM models with MOE and IE descriptors on the training set (cross-validation CV) and the external validation test set

Descriptors	Dataset	AUC %	BA %	Sensitivity %	Specificity %	MCC %
56 MOE + 6 IE	Internal CV	91.3	91.0	90.2	91.8	74.3
	External	90.7	90.7	88.9	92.5	74.5
162 MOE + 6 IE	Internal CV	90.2	88.9	88.1	89.7	68.7
	External	92.6	92.6	92.6	92.5	77.1