TABLE 2.
Clinical description and results obtained for solid organ transplant patientsa
Patient no. | Transplant type | Serological status of donor | IgG antibody titer (IU/ml) (wks post-TP) | Clinical symptoms | IgG-AI |
---|---|---|---|---|---|
1 | Heart | + | 21 (0) | 0.70 | |
273 (4) | Disseminated toxoplasmosisb | 0.58 | |||
364 (6) | Death | 0.48 | |||
2 | Heart | + | 753 (0) | None | 0.57 |
153 (2) | 0.46 | ||||
1,038 (11) | 0.81 | ||||
3 | Liver-lung | − | 212 (0) | None | 0.70 |
446 (10) | 0.60 | ||||
772 (12) | 0.50 | ||||
1,354 (19) | 0.52 | ||||
261 (24) | 0.52 | ||||
4 | Liver-kidney | − | 130 (0) | None | 0.72 |
2,260 (1) | 0.73 | ||||
>2,400 (3) | 0.78 | ||||
>2,400 (8) | 0.74 | ||||
5 | Heart | NA | 106 (0) | None | 0.50 |
820 (4) | 0.60 | ||||
1,360 (6) | 0.59 | ||||
1,110 (8) | 0.62 |
n = 5. Abbreviations: NA, not available; TP, transplantation.
Probably transmitted by the donor, as attested by anatomopathological signs of evolutive toxoplasmic myocarditis, detection of circulating parasites by PCR, and appearance of newly synthesized IgG isotypes by Western blot analysis (F. Robert-Gangneux et al., submitted for publication).