| NCD (−) | NCD (+) | total | |
| mutant 1 | N1 | N2 | N1 + N2 |
| nonmutant 1 | n1 | n2 | n1 + n2 |
| total | N1 + n1 | N2 + n2 | N1 + N2 + n1 + n2 |
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