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. 2022 Sep 23;17(10):2817–2827. doi: 10.1021/acschembio.2c00452

Table 3. List of the Inhibited Mutants and the Promoted Mutants.

	experiment no. 1			experiment no. 2			experiment no. 3
	log₂RP100K			log₂RP100K			log₂RP100K
sequence: 5′-N₁N₂N₃-3′/5′-N₄N₅N₆-3′	NCD (−)	NCD (+)	log FC	NCD (−)	NCD (+)	log FC	NCD (−)	NCD (+)	log FC
Inhibited Mutants
GUG GGU	6.71	8.68	1.97	5.93	9.64	3.71	6.87	7.73	0.86
GGU GUG	7.11	8.78	1.67	6.21	9.91	3.70	7.17	7.94	0.77
GGU GUA	6.64	8.78	2.14	6.13	10.02	3.88	6.91	7.78	0.88
GGU GGU	7.33	9.14	1.81	6.56	10.45	3.89	7.56	8.19	0.63
GGG GUU	7.34	9.07	1.73	6.92	10.12	3.20	7.68	8.28	0.60
GGG GUG	6.51	8.14	1.64	5.94	9.07	3.13	6.69	7.50	0.81
GGG GGU	7.18	8.73	1.55	6.54	9.83	3.29	7.28	8.11	0.82
GGG GGG	6.20	7.55	1.35	5.27	8.68	3.42	6.35	7.31	0.96
GGC GGU	6.77	9.13	2.36	6.26	10.57	4.30	6.99	7.93	0.94
GCA GGU	5.93	8.25	2.31	5.46	9.25	3.80	6.17	7.16	1.00
AGG GGU	5.96	8.36	2.40	5.70	9.62	3.93	6.28	7.33	1.06
Promoted Mutants
CGG AGU	7.53	5.62	–1.91	6.95	6.10	–0.85	7.63	5.24	–2.40
CGG AGC	6.12	4.20	–1.92	5.39	4.51	–0.88	6.13	4.08	–2.06