Table 2. ITC K_d Values for Modified Histone H3-Based Peptides Binding to the PHD-BRD Cassette of TRIM24, TRIM33α, or TRIM33β^a.

^aValues quoted from a representative run ± error of the curve fit. H3-peptide was injected (20 × 2 μL injections) into a cell containing protein in 50 mM HEPES buffer, pH 7.4, 150 mM NaCl. Raw heat effects for the data are shown in the Supporting Information. A heatmap display is used with “hot” colors corresponding to lower K_d values.