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. Author manuscript; available in PMC: 2023 Jul 6.
Published in final edited form as: J Am Chem Soc. 2022 Jun 23;144(26):11620–11625. doi: 10.1021/jacs.2c01929

Figure 1.

Figure 1.

In vitro screening identifies low-molecular-weight ligands that preferentially bind RNA. (A) Structures of compounds identified as hits with fluorescence at least three-fold above the background. (B) Schematic depiction of in vitro screening of low-molecular-weight compounds binding to total human RNA from MDA-MB-231 TNBC cells.