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. Author manuscript; available in PMC: 2022 Oct 25.
Published in final edited form as: J Thorac Cardiovasc Surg. 2020 Dec 13;163(4):e313–e328. doi: 10.1016/j.jtcvs.2020.11.160

FIGURE 1.

FIGURE 1.

VV variants and murine model of MPD methodology. A, Doubly deleted VV-YFP expressing membrane bound VV-IL-2 constructs. B, Illustrative display of the timing of experiments to assess day 14 end points and survival after inoculation with tumor and corresponding day 7 treatment. C, Hematoxylin–eosin stain of resected day 7 metastatic pleural disease (solid thin arrow), rib (dashed arrow), and intercostal muscle (bolded arrow) demonstrating successful tumor implantation in the MPD model (10× magnification).