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. Author manuscript; available in PMC: 2022 Oct 25.
Published in final edited form as: J Thorac Cardiovasc Surg. 2020 Dec 13;163(4):e313–e328. doi: 10.1016/j.jtcvs.2020.11.160

FIGURE 6.

FIGURE 6.

Intratumoral αβ TCR diversity correlates with tumor burden and T-cell infiltrate. To better understand the relationship of intratumoral TCR diversity and murine tumor response, tumor mass (A), day 14 bioluminescence (B), and intratumoral CD3+ T cells (C) were correlated with both TILVα and Vβ D50. Spearman correlation coefficient and P values are reported suggesting a negative correlation between TCRVαβ D50 and tumor burden (tumor mass and bioluminescence) and a positive correlation between TCR Vαβ D50 and TIL CD3+ counts.