Fig. 2.

Elevated expression of CBS in ductal cells of metastatic pancreatic cancer. (A). Immunohistochemical staining for CBS protein using tissue sections from 3 representative human PDAC tumors and from the matching non-tumor tissues (patient 1-2-3). (B). Immunohistochemistry of the lymph node metastases from the same patients (1-2-3). CBS protein in ductal cells is visualized by brown staining and indicated by the solid line arrows. Tumor sections of the indicated tissues were also stained with H&E to reveal tissue architecture. (Scale bars: 50 μm). Images are representative of 10 independent tissue samples. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)