Table 3.
Ka Values of Different Concentrations of Paeonol and Pae-Lips
| Concentration (μg/mL) | Group | Duodenum (× 10−4 cm/s) |
Jejunum (× 10−4 cm/s) |
Ileum (× 10−4 cm/s) |
Colon (× 10−4 cm/s) |
|---|---|---|---|---|---|
| 125 | Pae | 1.58 ± 0.16 | 1.80 ± 0.26 | 1.84 ± 0.06 | 1.69 ± 0.33 |
| Pae-Lips | 1.62 ± 0.23 | 1.81 ± 0.08 | 2.50 ± 0.05*** | 2.54 ± 0.17*** | |
| 250 | Pae | 1.36 ± 0.10 | 1.63 ± 0.004 | 1.47 ± 0.03 | 1.57 ± 0.04 |
| Pae-Lips | 1.75 ± 0.23 | 1.97 ± 0.11 | 2.19 ± 0.31* | 2.74 ± 0.18*** | |
| 500 | Pae | 1.39 ± 0.05 | 1.75 ± 0.03 | 1.86 ± 0.20 | 1.80 ± 0.29 |
| Pae-Lips | 1.47 ± 0.10 | 1.81 ± 0.21 | 2.02 ± 0.15 | 2.26 ± 0.22 |
Notes: the data were presented as the mean ± SD (n = 3). Compared with the paeonol group, *p < 0.05, ***p < 0.001.