Table 1.

The diagnostic criteria and curative effect evaluation of different diseases in patients enrolled in this study.

Classification of diseases	Diagnose criteria	Clinical remission	Clinical improvement
FC (19, 20)	Rome III Diagnostic Criteria for Functional Gastrointestinal Disorders. J Gastrointestin Liver Dis. (2006) 15:307–312. The New Rome IV Criteria fo Functional; Gastrointestinal Disorders in Infants and Toddlers. Pediatr Gastroenterol Hepatol Nutr. (2017) 20:1–13.	Spontaneous defecation ≥ 3 times per week	The clinical symptoms did not reach clinical remission, but improved significantly compared with before treatment
UC (21, 22)	Pediatric inflammatory bowel disease. World J Gastroenterol. (2006) 12:3204–3212. Inflammatory Bowel Disease in Children and Adolescents. JAMA Pediatr. (2015) 169:1053–1060.	PUCAI <10 points	PCDAI decreased by more than 10 points and PUCAI <30
CID (23)	Clinical approach and management of chronic diarrhea. Acta Med Indones. (2013) 45:157–165.	The number of defecations as well as the amount is normal	The number of defecation is reduced to 2~3 times/day
AC (15)	Fecal microbiota transplantation induces remission of infantile allergic colitis through gut microbiota re-establishment. World J Gastroenterol. (2017) 23:8570–81.	The blood stool returned to normal	Blood in the stool and diarrhea improved but were not normal
CDI (24)	Guidelines for diagnosis, treatment, and prevention of Clostridiodies difficile infections. Am J Gastroenterol. (2013) 108:478–99.	The clinical symptoms of diarrhea and hematochezia were completely normal	The clinical symptom for CDI better than before, but not up to the standard of cure
AD (25)	Japanese Guideline for Atopic Dermatitis 2014. Allergol Int. (2014) 63:377–98.	SCORAD index ≤5 and SCORAD decreased by more than 30 points	SCORAD index decreased by more than 10 points

FC, functional constipation; UC, ulcerative colitis; CID, chronic intractable diarrhea; AC, infantile allergic colitis; CDI, C.difficile infection; AD, atopic dermatitis.