Table 3.
Potential factors influencing FMT-related AEs occurrence.
| Item FMT procedures | Subgroup n = 74 | Number of AEs % (n/N) | Univariate p value | Multivariate | ||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | ||||
| Age group (n) | 0–36 mo >36 mo |
30.7 (12/39) 40.0 (14/35) |
0.032 | 0.836 | 0.121–2.564 | 0.526 |
| Disease type | UC Non-UC |
66.6 (8/12) 29.0 (18/62) |
0.0018 | 7.682 | 1.236–37.534 | 0.028 |
| Donors' genetic background | Relative Non-relative |
33.3 (10/30) 36.3 (16/44) |
0.632 | 1.28 | 0.736–2.52 | 0.432 |
| Route of administration | Enema Colonoscopy + Enema |
30.7 (16/52) 45.4 (10/22) |
0.036 | 1.832 | 0.899–5.212 | 0.126 |
| Gender | Male Female |
31.9 (15/47) 40.7 (11/27) |
0.186 | 1.872 | 0.436–8.634 | 0.48 |
| Donor | adult children | 42.8 (9/21) 32.1 (17/53) |
0.326 | 1.212 | 0.326–4.228 | 0.56 |
| Number of FMT infusions | ≤4 >4 |
60.0 (18/30) 18.1 (8/44) |
0.0005 | 9.768 | 1.912–14.321 | 0.021 |
UC, ulcerative colitis; FMT, fecal microbiota transplantation.