TABLE 1.
Summary of clinical information of medulloblastoma cohorts.
| GSE85217 dataset 1 | GSE85217 dataset 2 | GSE30074 | GSE21140 | SYSUCC cohort | |
|---|---|---|---|---|---|
| Case included (n) | 534 | 229 | 30 | 103 | 74 |
| Age (mean ± SD) | 5.6 (±8.01) | 8.6 (±7.39) | NA | 9.4 (±8.39) | 11.3 (±8.62) |
| Overall survival | N = 429 | N = 183 | N = 30 | NA | N = 74 |
| Year (mean ± SD) | 4.77 (±3.70) | 5.41 (±3.92) | 4.25 (±2.29) | — | 3.52 (±3.55) |
| Status (alive/dead) | 309/120 | 144/39 | 18/12 | — | 44/30 |
| Gender | N = 411 | N = 183 | N = 30 | N = 103 | N = 74 |
| Male | 288 | 132 | 19 | 63 | 52 |
| Female | 123 | 51 | 11 | 40 | 22 |
| Subgroup | N = 763 | NA | NA | N = 103 | NA |
| WNT | 70 | — | — | 8 | — |
| SHH | 223 | — | — | 33 | — |
| Non-WNT/SHH | 470 | — | — | 62 | — |
| Metastasis | N = 400 | N = 172 | NA | NA | NA |
| M0 | 273 | 124 | — | — | — |
| M1 | 127 | 48 | — | — | — |
Abbreviation: SHH, sonic hedgehog; WNT, wingless; M0, Non-Metastasis; M1, metastasis; SYSUCC, Sun Yat-sen University Cancer Center.