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. 2022 Sep 16;3:966034. doi: 10.3389/fpain.2022.966034

Figure 5.

Figure 5

Simulation of ten sessions of exposure therapy in the nullspace of marginal p(pain)=0.7, with ambiguous and imprecise likelihoods (A) and precise and accurate likelihoods (B). On the X-axis are the time steps, on the Y-axis the marginal probabilities of pain, and on the Z-axis the learning trials per time step. The combination of null space derived transition probabilities and an imprecise and ambiguous likelihood model (p(noxiouspain)=0.6, p(harmlesspain)=0.4, p(noxiouspain¯)=0.6, p(harmlesspain¯)=0.4) renders the repeated presentation of innocuous sensory information rather inefficient: inferred probabilities of pain remain within the range of the predefined marginal. When the likelihood model is precise and unambiguous (p(noxiouspain)=0.8, p(harmlesspain)=0.2, p(noxiouspain¯)=0.1, p(harmlesspain¯)=0.9), however, the presentation of harmless sensory information is more efficient in reducing the inferred probability of pain.