Table 2.

Comparison of cellular immune response among healthy controls, non-cirrhosis chronic liver disease patients, compensated cirrhosis, decompensated cirrhosis, and liver transplant recipients.

Cells	Healthy controls (n = 18)	Non-Cirrhosis CLD (n = 12)	P	Comp. Cirrhosis CLD (n = 19)	Decomp. Cirrhosis (n = 15)	P (post-hoc comparison)	LTR (15)	P
CD3%	60.46 ± 19.18	64.55 ± 15.76	0.54	60.15 ± 13.02	62.2 ± 15.36	0.92	64.22 ± 13.2	0.52
CD4%	46.58 ± 15.38	49.91 ± 9.7	0.51	49.6 ± 18.15	48.14 ± 14.2	0.85	52.44 ± 10.38	0.21
CD4 Central memory%	37.01 ± 14.72	48.63 ± 15.18	0.04	37.8 ± 10.65	45.52 ± 10.97	0.1	42.5 ± 12.84	0.26
CD4 Naïve%	20.11 ± 9.41	15.97 ± 7.74	0.21	21.64 ± 14.95	11.76 ± 9.92	0.04 (HC vs CC-0.69; HC vs DC-0.05 CC vs DC-0.02)	32.26 ± 13.64	0.005
CD4 effector memory%	28 ± 6.62	26.25 ± 7.61	0.51	33.03 ± 14.82	37.53 ± 8.52	0.05 (HC vs CC-0.16; HC vs DC-0.01 CC vs DC-0.23)	21 ± 13.34	0.058
CD4 effector %	16.81 ± 9.7	9.1 ± 6.51	0.02	9.89 ± 11.5	4.68 ± 4.1	0.002 (HC vs CC-0.03; HC vs DC-<0.001 CC vs DC-0.1)	3.86 ± 1.89	<0.001
CD8%	34.78 ± 13.17	38.03 ± 10.62	0.47	38.22 ± 17.05	41.32 ± 14.78	0.47	40.78 ± 10.46	0.16
CD8 CENTRAL MEMORY%	17.82 ± 8.18	18.62 ± 10.16	0.81	15.23 ± 7.04	23.13 ± 11.22	0.04 (HC vs CC-0.37; HC vs DC-0.09 CC vs DC-0.01	21.62 ± 14.43	0.35
CD8NAIVE%	24.41 ± 8.33	21.83 ± 5.52	0.35	28.88 ± 14.2	21.53 ± 4.64	0.11	43.94 ± 20.31	0.001
CD8 EFFECTOR MEMORY%	18.47 ± 8.36	14.45 ± 7.65	0.19	18.94 ± 9.92	18.97 ± 6.26	0.98	16.61 ± 8.74	0.53
CD8 EFFECTOR%	39.22 ± 8.82	45.16 ± 12.91	0.14	36.95 ± 13.18	36.34 ± 10.45	0.72	17.8 ± 11.34	<0.001
B CELLS%	16.23 ± 9.33	11.14 ± 4.03	0.08	21.15 ± 10.53	10.86 ± 7.61	0.01 (HC vs CC-0.11; HC vs DC-0.11 CC vs DC-0.003)	11.11 ± 6.8	0.09
B MEMORY CELLS %	3.43 ± 1.46	3.36 ± 1.42	0.9	3 ± 1.25	2.34 ± 1.24	0.08 (HC vs CC-0.32; HC vs DC-0.02 CC vs DC-0.16)	4.08 ± 1.7	0.25

CLD, chronic liver disease; CC, compensated cirrhosis; DC, decompensated cirrhosis; HC, healthy controls; LTR, liver transplant recipients.

P is in comparison with healthy control group.