Table 2:
Differential gene expression analyses of interleukins in skin diseases
| Disease | Interleukins | Interleukins for gp130 (IL6ST) complex receptors | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| IL-31 | IL-4 | IL-13 | OSM | IL-6 | LIF | CNTF | CTF1 | IL-11 | IL-27 | |
| Psoriasis | −0.1 | −0.9 | 0.4 | 3.5 | 2.2 | −1.6 | −0.9 | −0.6 | 0.6 | 0.4 |
| AD | 0.2 | 0.2 | 3.6 | 2.3 | 2.1 | −1.7 | 0.3 | 0.04 | 0.4 | −0.4 |
| CTCL | 0.09 | 1.4 | 1.3 | 2.1 | −2.2 | −0.8 | 0.4 | 0.4 | 0.5 | 1.3 |
| Imiquimod | N.d. | 0.05 | −1.4 | 1.8 | 1.4 | 0.8 | −0.3 | −0.5 | 0.4 | −0.06 |
Differential gene expression analyses of interleukins in inflammatory skin conditions (inflamed skin vs normal skin). The numbers indicate the expression of genes that are up- or down-regulated for inflamed skin samples versus normal skin (log 2 scale). N.d. indicates not detected. The analyses were performed with R package DESeq2.