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. 2022 Oct 14;12(1):38–55. doi: 10.1089/wound.2020.1348

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© Bo Yuan et al. 2023; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License [CC-BY-NC] (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited.

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Figure 4. — Collagen examination of human hypertrophic scars at different stages by Masson's staining. In normal skin, the collagen arrangement is loose (a). However, in hypertrophic scars, a large amount of collagen is deposited around the microvasculature (b). In RSs, the microvessels are partially or totally occluded, and the collagen density is decreased (c). In mature scars, the microvessels and collagen density are comparable to those of normal skin (d). The red arrows indicate the microvessels. Color images are available online.