FIG. 4.

(A) Serum opsonic activity for pneumococcus type 14 in infants with SCD immunized at 2, 4, and 6 months of age. Open symbols represent infants with low (<1.0 μg/ml) preimmunization antibody levels. Closed symbols represent infants with high (>1.0 μg/ml) preimmunization antibody levels. The interrupted line indicates the data for negative controls (14.4%). (B) Comparison of serum opsonic activity for pneumococcus type 14 between infants with SCD and control infants immunized starting at 2 months of age. The lower and upper boundaries of the box indicate the 25th and 75th percentiles, respectively. A continuous line within the box marks the median; a dotted line marks the mean. Error bars indicate the 90th and 10th percentiles. Open symbols represent data outside 10th and 90th percentiles.